Rachel Brown (Whitehall) and Ashly Schuitema (WMC) dominated the front court, with Brown tallying 17 kills and Schuitema with 12.
Schuitema also recorded 11 aces and 11 digs on the evening.
Lindsey Jacobs (Ravenna) contributed 37 assists to go along with five kills, two aces, and two blocks. Marissa Hassevoort (Fruitport) added 19 digs.
The Jayhawks are back in action on Thursday when they host Glen Oaks.