With the victories, the Red Devils advance to take on Portland St. Patrick at 3 p.m. on Tuesday at Central Michigan University.
In the semifinal game, Maddi Bosset and Kylie Gould each had three hits including a double and home run each to lead the offense.
Holton finished with 19 hits total in the blowout victory.
In the final, Abbie Fowler went 4-for-4 at the plate to lead the Holton offense while Ryan Robins had three hits including a home run.
Kylie Gould picked up the win on the mound while Kennedy Greene finished with two hits.
The Red Devils are now 35-6 overall on the season.