Holton quarterback Austin Fowler completed 12-of-20 passes for 157 yards and one touchdown. He also rushed for one touchdown.
Rice Robins finished with 50 yards in receptions and one touchdown and Bret Hosmer had 56 receiving yards.
Kaleb Nichols was the leading rusher with 57 yards and one touchdown. Kevin Erickson had 55 yards in offense, including 35 on receptions.
Dylan Cartwright led with the Red Devils defense with 11 tackles, Hosmer and Robins each had seven tackles and Jared Coburn, Fowler and Nichols had six each.
Holton will travel to White Cloud next week.