Ella Muskovin piled on the aces with 12, while Claire LaVigne added 12 assists, nine aces and five digs.
Natalie Rich posted eight aces. Lindsay Ladd and Clare Carlton threw in six kills and five kills respectively.
Muskegon Catholic Central (3-5) will open the conference season on Thursday at home against West Michigan Aviation Academy.
Muskegon will also kick off league play with a home match against Reeths-Puffer on Thursday.