The non-conference game was played at Orchard View.
Some big Orchard View three-point baskets left the Lions with too much ground to make up. In all, the Cardinals made 10 shots from beyond the 3-point line.
Delaney Oakes finished with 23 points and Keith McAllister had 22 to lead OV.
Bryce Decker paced the Lions’ offense with a double-double of 17 points and 10 rebounds. Josiah Long and Dyllan Bazzett added 14 and 11 points, respectively.
Newaygo (1-3) will be at home on Friday against Kent City.
Orchard View (1-2) is set to travel to Manistee on Thursday.