Ludington earned a split when the Orioles recorded a 94-79 victory over Alma.
The Lakers picked up four first-place finishes and recorded two personal bests.
Noah Fletcher, a sophomore, was first in the 200-yard freestyle and 100-yard butterfly, both of which made the state cuts.
Another sophomore, Ryan Fisher, won the 100-yard backstroke. Jonah VanDreumel was first in the 1-meter diving, while Alex Strauss won the 500 free and was third in the 200 IM.
Kyle Eecker finished third in the 100 free and lowered his personal best time by 3.8 seconds.
Ryan Bonney, a junior, recorded a personal best in both the 50 and 100 free races. Lando Mendoza had a personal best in the 100 free.
Ludington picked up one first place, that coming from Lucas Peterson in the 200 individual medley and also swam a leg on the 200 freestyle relay.
The Orioles also had three second places recorded by Ignacio Molina in the 50 freestyle, 200 free relay and 100 breaststroke.
Gavin Smith was second in the 500 freestyle and swam a leg on the 200 freestyle relay.
Other second-place finishes were recorded by Dylan Sniegowski in th 200 IM relay, Ian Lundberg in the diving competition and Kyle Wendt in the 200 freestyle relay.
Ludington competes in the Manistee tri-meet on Saturday.