The Big Reds had a balanced scoring attack with three players in double digits.
Mariah Sain led Muskegon with a game-high 14 points. Ty’Veonna Davis tossed in 11 points while Aaliyah Winston chipped in with 10 points.
Muskegon raced out to a 22-8 lead after the first eight minutes of action and led 31-14 at the half.
The Big Reds put the game away in the third period by outscoring Holland 25-2. Neither team generated much offense in the final eight minutes as the Dutch managed a 5-4 advantage.
Muskegon (8-5, 6-0) will host Mona Shores on Friday.