The match was played at Mason County Eastern.
The Crusaders escaped with the victory in three sets, 26-24, 25-19, 28-26.
Claire LaVigne led the way with 24 digs, 16 assists, 11 kills and two aces. Natalie Rich followed with six aces on the night.
Elana LaGuire added 16 digs and four aces and Lindsay Ladd had six kills and a block.
Calvary Christian’s Ella Dykman had 19 digs, 15 kills and an ace, while Kamea Sutherland had 15 digs, eight kills and four aces.
Marissa Tyler also contributed 27 assists and 16 digs for the Eagles.
Muskegon Catholic (16-18) will head to McBain on Tuesday for the regional semifinal round. The Crusaders will face Mount Pleasant Sacred Heart.