Knizacky connected on TD passes of 34 yards to Dylan Hearns and six and 24 yards to Ryan Mount.
Cody Soberalski added TD runs of five and eight yards for MCC and Austin Tyndall scored on a nine yard run for the Spartans.
Austin MacDougall led the MCC defense with seven tackles.
MCC had 400 total yards with 292 yards rushing and 108 passing.
The Spartans improved to 4-2 on the season.