The Norse held a convincing 21-12 lead by the end of the first half, and shut down the Crusaders from making up any kind of ground.
Jenn Francis got hot for the Norse, scoring 14 points including four three pointers while Josee Cooke scored 10 points and grabbed six rebounds.
Scoring for the Crusaders was Grace Staniforth and Claire LaVigne with 10 and nine points, respectively.
North Muskegon moves to 1-1 and will travel to Whitehall on Thursday to battle the Vikings.
Muskegon Catholic drops to 0-2 and will look for their first win when they host Manistee on Friday.