The Turtles swam strong and won 11 of the 12 events.
The 200 medley relay team of Delaney Buckner, Susie Van Baale, Robyn Hunt and Sydney Sytsema won with a time of 2:02.26.
The team of Naomi Huttenga, Maria Eenigenburg, Sophia Zzwambazza and Marilyn Gaston claimed the 200 free relay with a time of 1:55.99.
The 400 free relay team of Hunt, Sytsema, Huttenga and Buckner also took first-place with a time of 4:02.82.
Sytsema (50 free, 100 free), Hunt (200 free, 500 free) and Buckner (100 fly, 100 back) were double winners on the evening.
Huttenga and Van Baale posted first-place finishes in the 200IM and 100 breast respectively.
The Turtles (3-1, 1-0) will face a tough conference matchup when they travel to state-ranked Zeeland on Tuesday.